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Breaking News: Parkinson's Disease Biomarker Found

In an enormous leap forward in the understanding of Parkinson’s disease (PD), researchers have discovered a new tool that can reveal a key pathology of the disease: abnormal alpha-synuclein — known as the “Parkinson’s protein” — in brain and body cells. The breakthrough, announced last night as it was published in the scientific journal The Lancet Neurology, opens a new chapter for research, with the promise of a future where every person living with Parkinson’s can expect improved care and treatments — and newly diagnosed individuals may never advance to full-blown symptoms.   

https://www.michaeljfox.org/news/breaking-news-parkinsons-disease-biomarker-found?

phkrause

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A man with Parkinson's who was unable to walk without falling is enjoying Sunday strolls again thanks to a spine implant

A man diagnosed with Parkinson's disease almost 30 years ago who could barely walk on his own can now climb stairs and go out independently again thanks to a potentially revolutionary device implanted in his spinal cord.

https://www.insider.com/spine-stimulator-implant-helps-parkinsons-disease-walk-2023-11

Spinal implant helps man with advanced Parkinson’s to walk without falling

phkrause

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🧠 Brain pacemaker for Parkinson's
 
Illustration of a brain on blueprint paper with various areas called out.
 

Illustration: Aïda Amer/Axios

 

An implant that responds to brain signals in real time was shown to ease symptoms of Parkinson's disease instantaneously in a limited trial of whether the technology can help patients as they go about their daily lives, Axios' Maya Goldman writes.

  • Why it matters: It's an example of how deep brain stimulation combined with artificial intelligence can track a patient's brain activity for tremors, limb stiffness and other features of a condition diagnosed in almost 90,000 people in the U.S. each year.

How it works: The approach developed by UC San Francisco researchers differs from conventional deep brain stimulation treatments that deliver constant electric currents and can lead to unwanted side effects.

  • It uses algorithms that sense motor symptoms and produce a personally tailored level of brain stimulation to prevent them.
  • The new technology reduced involuntary movements and other symptoms by 50% in four patients who had Parkinson's for at least 10 years, researchers wrote yesterday in Nature.

Reality check: The technology doesn't change the trajectory of the underlying disease.

phkrause

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Parkinson's Disease May Soon Outpace Dementia: What to Know

April 11, 2025 – Two incurable diseases loom over our aging populace: Parkinson's and Alzheimer's. Right now, Alzheimer's is more common and seems a more widespread concern than the relatively narrow shadow cast by Parkinson's.

https://www.webmd.com/parkinsons-disease/news/20250411/parkinsons-disease-may-soon-outpace-dementia-what-to-know?

phkrause

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What to Know About Parkinson’s Symptoms in Adults

Parkinson’s disease starts in the brain. Certain nerve cells break down or die. As a result, the levels of dopamine, a chemical in your brain, begin to fall. When your dopamine levels decrease, it causes your brain to act in unusual ways and leads to impaired movement, among other things.

https://www.webmd.com/healthy-aging/what-to-know-about-parkinsons-symptoms-in-adults?

phkrause

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phkrause

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What Is Parkinson's Disease?

Parkinson's disease is an illness that affects the part of your brain that controls how you move your body. It can come on so slowly that you don't even notice it at first. But over time, what starts as a little shakiness in your hand can have an impact on how you walk, talk, sleep, and think.

https://www.webmd.com/parkinsons-disease/parkinsons-disease-overview?

phkrause

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Carrying on a Father's Legacy

The daughter of a Parkinson's disease activist helps others realize they're not alone.

https://www.brainandlife.org/articles/carrying-on-fathers-legacy?

Staying Active Can Slow Cognitive Decline in Parkinson’s Disease

If you have Parkinson’s disease (PD) and are staying active, you’re likely doing yourself a big favor.

https://www.brainandlife.org/articles/staying-active-slow-cognitive-decline-parkinsons-disease?

Smartphone Apps Can Help Manage Parkinson’s, Migraines, Epilepsy, and More

Stacee Hawkins credits a health-changing aha moment to a smartphone app. Linked to her smartwatch, StrivePD, from Rune Labs, automatically detects and records tremors and muscle spasms called dyskinesia in addition to tracking her diet, physical activity, sleep, medications, stress, and more.

https://www.brainandlife.org/articles/smartphone-apps-manage-parkinsons-migraine-epilepsy-more?

phkrause

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Fighting Parkinson's with ping-pong
mail?url=https%3A%2F%2Fimages.axios.com%
Parkinson's patients take to the ping-pong tables on a recent Tuesday in Southeast Portland. GIF: Kale Williams/Axios

In Portland, Ore., some Parkinson's patients have found an unlikely ally in their battle against the disease: ping-pong paddles.

  • Why it matters: Table tennis is emerging as a surprising source of therapy and community for those with Parkinson's disease — boosting balance, easing tremors and creating meaningful connection, Axios Portland's Kale Williams reports.

🧠 The big picture: Ping Pong Parkinson, an international nonprofit propelling the movement, says playing can stimulate brain activity, improve motor control and sharpen reflexes in people with Parkinson's.

  • Some studies suggest these benefits can spill into daily life.

Zoom in: Each Tuesday morning, about a dozen players rally at the Portland Table Tennis Club, where guided by coaches they serve, slam and laugh their way through fast-paced games.

  • Sharon Bergman — who was diagnosed with Parkinson's in 2019 — says she feels like a different person when she steps up to the ping-pong table. "When I play ping-pong, I forget I have Parkinson's. ... It brings a lot of joy."
  • "You have to move fast, deciding what kind of shot to hit, whether it's forehand or backhand," says Phil Bernstein, who was diagnosed in 2023. "That's something that Parkinson's takes from you."

💡 At Parkinson's Resources of Oregon in Beaverton, coach Rob Solomon has seen the shift firsthand.

  • "Some of their tremors are incredibly sad, and then they get up to the table and their hand is just solid," he says.

Beyond the physical, Solomon adds: "I've never seen the kind of cohesion among the players that we have here. It's because they're all doing it together."

ps:I've heard about this before!!

phkrause

Read Isaiah 10:1-13
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phkrause

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