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Researchers at Mass General Brigham have uncovered evidence that the thymus, a small immune system organ long thought to lose its importance after childhood, may play a major role in adult health. Two new studies found that adults with healthier thymuses were more likely to live longer and less likely to develop serious diseases. The research also suggests that thymic health may influence how well cancer patients respond to immunotherapy. The findings were published in two papers in the same issue of Nature and challenge decades of assumptions about the thymus. The results indicate that the organ remains important throughout adulthood and could eventually help guide disease prevention strategies and cancer treatment decisions. "The thymus has been overlooked for decades and may be a missing piece in explaining why people age differently, and why cancer treatments fail in some patients," said Hugo Aerts, PhD, corresponding author on the papers and director of the Artificial Intelligence in Medicine (AIM) Program at Mass General Brigham. "Our findings suggest thymic health deserves much more attention and may open new avenues for understanding how to protect the immune system as we age." What the Thymus Does Located in the chest, the thymus helps train T cells, a type of immune cell that helps defend the body against infections and disease. Because the organ gradually shrinks after puberty and produces fewer new T cells over time, many scientists assumed it played only a limited role in adult health. As a result, the thymus has received relatively little attention in large population studies. Earlier research connected T cell diversity to aging and declining immune function, but those studies were typically small and focused on blood samples. The new research took a much broader approach. Investigators analyzed data from more than 25,000 adults participating in a national lung cancer screening trial, along with more than 2,500 people enrolled in the Framingham Heart Study, a long-running study that tracks the health of generally healthy adults. https://www.sciencedaily.com/releases/2026/06/260601025352.htm

A new three-year study from researchers at The University of Texas at Dallas' Center for BrainHealth (CBH) suggests that getting older does not automatically mean losing mental sharpness. Instead, the findings indicate that brain health and cognitive abilities can continue to improve throughout life. The research, published in Scientific Reports, a Nature journal, draws on data from The BrainHealth Project (BHP), an initiative launched by CBH in 2020 to better understand how people can strengthen and optimize brain health across the lifespan. Researchers tracked 3,966 adults ranging in age from 19 to 94. This group represented roughly one-fifth of all BrainHealth Project participants. Over the course of three years, participants completed brief training activities that required only five to 15 minutes per day. BrainHealth Index Tracks Changes Over Time To evaluate changes in brain health and performance, the team used the BrainHealth Index (BHI), a patent-pending assessment developed by CBH researchers and first introduced in a 2021 pilot study. The BHI is designed to detect both improvements and declines in brain health. It measures three primary areas: clarity, emotional balance, and connectedness to people and purpose. "The BrainHealth Index brings together about 20 metrics, including validated gold-standard measures like the Pittsburgh Sleep Quality Index and the Oxford Happiness Questionnaire, as well as tasks designed at the Center for BrainHealth to focus on more complex thinking skills," said Lori Cook MS'02, PhD'09, CBH director of clinical research and corresponding author of the Scientific Reports study. "This battery of assessments produces insights into individual brain health and change over time. Progress is measured by comparing results with participants' own earlier scores." Cook, who also serves as an adjunct assistant professor in the School of Behavioral and Brain Sciences, said the findings challenge common assumptions about aging and cognition. "Every brain is as unique as a fingerprint and has potential for growth," Cook said. "This study challenges the prevailing narrative of inevitable cognitive decline, suggesting instead that brain health can be proactively cultivated at any age." Brain Improvement Seen Across All Ages According to the researchers, positive changes were observed even among participants in their 80s, showing that efforts to improve brain health can be beneficial long before symptoms or disease appear and can remain effective later in life. "For too long, we've operated under the outdated notion that we need to wait until something bad happens to our brains before we do anything for them," said Sandra Bond Chapman PhD'86, senior author of the study, CBH chief director and Dee Wyly Distinguished University Chair for BrainHealth. "This study reminds us that our brain is not defined by age -- it is defined by possibility." One of the study's most notable findings involved participants who started with the lowest BrainHealth Index scores. This group experienced the largest improvements over time. "Those who are starting at the lowest level appear to have the most opportunity for growth and may be coming in with more preexisting concerns," Cook said. "As such, they may be more motivated to invest the time needed to see more growth potential. But it is noteworthy that we saw measurable growth even in those entering as high performers." https://www.sciencedaily.com/releases/2026/06/260613034222.htm

For centuries, losing human teeth meant living with a permanent gap in your smile or relying on artificial replacements. But a groundbreaking discovery by Japanese researchers could change this reality forever, offering the possibility of naturally regrowing teeth where they’ve been lost. Led by Dr. Katsu Takahashi at Kyoto University Graduate School of Medicine, scientists have developed a drug that could stimulate the body to grow new teeth—a breakthrough that might one day make dental implants and dentures a thing of the past. https://japandaily.jp/regrowing-human-teeth-ending-dental-implants/ -------------------------------------------------------------------------------------------------------------------- Tooth regeneration therapy enters first human clinical trials in Japan Synopsis A groundbreaking human trial in Japan is exploring a revolutionary treatment to regrow teeth. Researchers have identified a way to activate dormant tooth buds, potentially offering a natural solution for tooth loss. Early results are promising, with a drug aiming for a 2030 release, heralding a new era in dental care. In Japan researchers have taken the first step of their kind by starting the first-ever human trial in a treatment that aims to help grow teeth. In May 2026, the trial is progressing with a cautious optimism, and are aiming to release the drug in 2030. Many people across the globe are who suffer from teeth loss as a result of the effects of aging, injury or genetics, this breakthrough can revolutionize dental treatment. Read more at: https://economictimes.indiatimes.com/news/international/us/japanese-scientists-begin-human-trials-for-tooth-regrowth-drug/articleshow/130710567.cms?utm_source=contentofinterest&utm_medium=text&utm_campaign=cppst

For generations, scientists have viewed the inability to regrow lost body parts as one of the fundamental limitations of humans and other mammals. While creatures such as salamanders can regenerate entire limbs, humans typically heal injuries by forming scar tissue. New research from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS), however, suggests that regenerative abilities may not be entirely absent in mammals. Instead, they could be hidden within the body's normal healing machinery, waiting to be activated under the right conditions. "Why some animals can regenerate and others, particularly humans, can't is a big question that has been asked since Aristotle," said Dr. Ken Muneoka, a professor in the VMBS' Department of Veterinary Physiology & Pharmacology (VTPP). "I've spent my career trying to understand that." In a study published in Nature Communications, Muneoka and colleagues describe a new two-step treatment that enabled the regeneration of bone, joint structures, and ligaments. Although the regrown tissues were not perfect replicas of the originals, the researchers believe the approach could eventually help reduce scarring and improve tissue repair after amputations. https://www.sciencedaily.com/releases/2026/06/260618041508.htm

Researchers in Brazil have created a new biomaterial made from jackfruit latex, pomegranate peel extract, and simvastatin (a statin-based medication) that could offer a more effective way to treat periodontitis, a serious form of gum disease. The team, from the Faculty of Medical and Health Sciences (FCMS) at the Pontifical Catholic University of São Paulo (PUC-SP) in Sorocaba, developed the material as part of an effort to improve treatment options for a condition that affects the tissues supporting the teeth. Periodontitis is a chronic inflammatory disease caused by infection. Over time, it can destroy the structures that hold teeth in place, leading to bone loss and reduced attachment between teeth and surrounding tissues. Current treatments are designed to control infection and inflammation, but they generally do little to regenerate damaged periodontal tissue. Other approaches, including guided tissue regeneration and bone grafting, have been explored, but their results can vary and are often difficult to predict. https://www.sciencedaily.com/releases/2026/06/260618041508.htm ------------------------------------------------------------ I have a Jackfruit tree in my yard. The fruit is the size of two smaller bowling balls. It is very popular here. When one fruit is ready, we cut it down and cut it up into pieces, then share with the neighbors. Nothing is waisted. Even the seed (about the size of dates) are boiled and eaten. Gum disease is not a problem here.

✈️ Parting shot! Photo: Michael Meath Reader Michael Meath of Lewes, Del., sends us this view from the skies: "Flying my Cessna 172 over Cape Henlopen State Park and the Delaware Bay at sunset."

Before dawn in Nigeria’s Middle Belt, the roosters do not get to finish. The men arrive with rifles and machetes while the village is still folded in sleep, and by… The post U.S. Brands Nigeria a Religious Freedom Violator as Christian Death Toll Climbs appeared first on ReligiousLiberty.TV. View the full article

Bill C-9, the *Combatting Hate Act*, has cleared the Canadian Senate, instituting expansive new criminal penalties for hate-motivated activities. The legislation creates a specific criminal offense for intimidating or obstructing… The post Canada’s "Combatting Hate Act": Legislative Expansion of Criminal Speech Laws appeared first on ReligiousLiberty.TV. View the full article

The United States Court of Appeals for the Fifth Circuit has reversed a district court decision that dismissed a lawsuit filed by the Lutheran Church-Missouri Synod (LCMS) against Concordia University… The post Fifth Circuit Reverses Dismissal in Lutheran Church-Missouri Synod Governance Dispute appeared first on ReligiousLiberty.TV. View the full article

In 1890 the Supreme Court knew exactly what religion was, which should have been the first warning. Certainty on a question like this is usually the sound of a man… The post What is "Religion" anyway? appeared first on ReligiousLiberty.TV. View the full article

In April, Gov. Ned Lamont signed a bill that cut a hole in Connecticut’s own Religious Freedom Restoration Act. House Bill 5044, sold as a vaccine-standards measure, declares that the… The post Conscience Is Not a Coupon appeared first on ReligiousLiberty.TV. View the full article

On the evening of June 5, 2026, in a chapel in Riverside, the president of La Sierra University stood before seven graduates and told them, “I am La Sierra,” and… The post The Shield They Are Dismantling appeared first on ReligiousLiberty.TV. View the full article

Three Protestant bodies spent one week at war over the body. The only church adding members is the one that refused to hold the argument. The Southern Baptist Convention reached… The post Everybody’s Wrong, and Rome Is Filling Up appeared first on ReligiousLiberty.TV. View the full article

The big picture: The intersection of faith and public policy is tightening. Courts and legislatures remain the primary battlegrounds, with a distinct shift toward administrative action and conscience protections as… The post RELIGIOUS LIBERTY: A WEEKLY BRIEFING appeared first on ReligiousLiberty.TV. View the full article

Chicago Co-Founder Walt Parazaider Dies After Bout With Alzheimer’s Disease https://www.thedailybeast.com/founding-member-of-chicago-walter-parazaider-dead-at-81-from-tragic-illness/?

Gene Shalit, longtime ‘Today’ show movie critic with bushy hair and massive mustache, dies at 100 https://apnews.com/article/gene-shalit-dies-b8ed6f4b7054e530e5fba9a808902cca?

Ford recalls more than 250,000 Focus models because engines can stall unexpectedly Ford is recalling more than 250,000 vehicles that were incorrectly repaired under a previous recall meant to fix a problem that caused the engine to stall while driving. https://apnews.com/article/ford-focus-recall-safety-engine-stall-21edfd428bacbf9c9f5a45c62e45c1d1? Nara Organics recalls baby formula sold at Target after multistate infant botulism outbreak SAN FRANCISCO (AP) — Nara Organics recalled its organic baby formula sold nationwide in Target stores and online Saturday after a multistate outbreak of infant botulism, federal authorities said. https://apnews.com/article/infant-botulism-byheart-formula-outbreak-90a0a08910d1162d77b9eb65d63ed667?